473 research outputs found
Computing Topology Preservation of RBF Transformations for Landmark-Based Image Registration
In image registration, a proper transformation should be topology preserving.
Especially for landmark-based image registration, if the displacement of one
landmark is larger enough than those of neighbourhood landmarks, topology
violation will be occurred. This paper aim to analyse the topology preservation
of some Radial Basis Functions (RBFs) which are used to model deformations in
image registration. Mat\'{e}rn functions are quite common in the statistic
literature (see, e.g. \cite{Matern86,Stein99}). In this paper, we use them to
solve the landmark-based image registration problem. We present the topology
preservation properties of RBFs in one landmark and four landmarks model
respectively. Numerical results of three kinds of Mat\'{e}rn transformations
are compared with results of Gaussian, Wendland's, and Wu's functions
Global well-posedness for a nonlocal Gross-Pitaevskii equation with non-zero condition at infinity
We study the Gross-Pitaevskii equation involving a nonlocal interaction
potential. Our aim is to give sufficient conditions that cover a variety of
nonlocal interactions such that the associated Cauchy problem is globally
well-posed with non-zero boundary condition at infinity, in any dimension. We
focus on even potentials that are positive definite or positive tempered
distributions.Comment: Communications in Partial Differential Equations (2010
Extensive weight loss reveals distinct gene expression changes in human subcutaneous and visceral adipose tissue
Weight loss has been shown to significantly improve Adipose tissue (AT) function, however changes in AT gene expression profiles particularly in visceral AT (VAT) have not been systematically studied. Here, we tested the hypothesis that extensive weight loss in response to bariatric surgery (BS) causes AT gene expression changes, which may affect energy and lipid metabolism, inflammation and secretory function of AT. We assessed gene expression changes by whole genome expression chips in AT samples obtained from six morbidly obese individuals, who underwent a two step BS
strategy with sleeve gastrectomy as initial and a Roux-en-Y gastric bypass as second step surgery after 12 ± 2 months. Global gene expression differences in VAT and subcutaneous (S)AT were analyzed through the use of genome-scale metabolic model (GEM) for adipocytes. Significantly altered gene expressions were PCR-validated in 16 individuals, which also underwent a two-step surgery intervention. We found increased expression of cell death-inducing DFFA-like effector a
(CIDEA), involved in formation of lipid droplets in both fat depots in response to significant weight loss. We observed that expression of the genes associated with metabolic reactions involved in NAD+, glutathione and branched chain amino acid metabolism are significantly increased in AT
depots after surgery-induced weight loss
Extensive weight loss reveals distinct gene expression changes in human subcutaneous and visceral adipose tissue
Weight loss has been shown to significantly improve Adipose tissue (AT) function, however changes in AT gene expression profiles particularly in visceral AT (VAT) have not been systematically studied. Here, we tested the hypothesis that extensive weight loss in response to bariatric surgery (BS) causes AT gene expression changes, which may affect energy and lipid metabolism, inflammation and secretory function of AT. We assessed gene expression changes by whole genome expression chips in AT samples obtained from six morbidly obese individuals, who underwent a two step BS
strategy with sleeve gastrectomy as initial and a Roux-en-Y gastric bypass as second step surgery after 12 ± 2 months. Global gene expression differences in VAT and subcutaneous (S)AT were analyzed through the use of genome-scale metabolic model (GEM) for adipocytes. Significantly altered gene expressions were PCR-validated in 16 individuals, which also underwent a two-step surgery intervention. We found increased expression of cell death-inducing DFFA-like effector a
(CIDEA), involved in formation of lipid droplets in both fat depots in response to significant weight loss. We observed that expression of the genes associated with metabolic reactions involved in NAD+, glutathione and branched chain amino acid metabolism are significantly increased in AT
depots after surgery-induced weight loss
Masked ambiguity – Emotion identification in schizophrenia and major depressive disorder
Both patients with schizophrenia and with a major depressive disorder (MDD) display deficits in identifying facial expressions of emotion during acute phases of their illness. However, specific deficit patterns have not yet been reliably demonstrated. Tasks that employ emotionally ambiguous stimuli have recently shown distinct deficit patterns in patients with schizophrenia compared to other mental disorders as well as healthy controls. We here investigate whether a task which uses an ambiguous Japanese (Noh) mask and a corresponding human stimulus generates distinctive emotion attribution patterns in thirty-two Caucasian patients with schizophrenia, matched MDD patients and healthy controls. Results show that patients with schizophrenia displayed reaction time disadvantages compared to healthy controls while identifying sadness and anger. MDD patients were more likely to label stimuli with basic compared to subtle emotional expressions. Moreover, they showed more difficulties assigning emotions to the human stimulus than to the Noh mask. IQ, age and cognitive functioning did not modulate these results. Because overall group differences were not observed, this task is not suitable for diagnosing patients. However, the subtle differences that did emerge might give therapists handles that can be used in therapy.Action Contro
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